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1

Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720

Shin Enosawa, Seiichi Suzuki, Toshihiro Kakefuda, Xiao-Kang Li, Hiroshi Amemiya

Journal:

Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 575 KB

english, 1996

2

An immunosuppressive regimen using FTY720 combined with cyclosporin in canine kidney transplantation

S. Suzuki, Toshihiro Kakefuda, Hiroshi Amemiya, Kenji Chiba, Yukio Hoshino, Takafumi Kawaguchi, Hirotoshi Kataoka, Fazlur Rahman

Journal:

Transplant International

Year:

1998

Language:

english

File:

PDF, 297 KB

english, 1998

3

Association of contrast-induced acute kidney injury with long-term cardiovascular events in acute coronary syndrome patients with chronic kidney disease undergoing emergent percutaneous coronary intervention

Watabe, Hiroaki, Sato, Akira, Hoshi, Tomoya, Takeyasu, Noriyuki, Abe, Daisuke, Akiyama, Daiki, Kakefuda, Yuki, Nishina, Hidetaka, Noguchi, Yuichi, Aonuma, Kazutaka

Journal:

International Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 588 KB

english, 2014

4

The Isolation of the Mitotic Apparatus from Mammalian Cells in Culture

Jesse E. Sisken, Elaina Wilkes, Grace M. Donnelly and Tsuyoshi Kakefuda

Journal:

The Journal of Cell Biology

Year:

1967

Language:

english

File:

PDF, 2.01 MB

english, 1967

5

Role of molecular conformation in determining the electrophoretic properties of polynucleotides in agarose-acrylamide gels. II

Dingman, C. Wesley, Fisher, M. Patricia, Kakefuda, T.

Journal:

Year:

1972

Language:

english

File:

PDF, 2.33 MB

english, 1972

6

Annual and seasonal home range characteristics of female Asiatic black bears in Karuizawa, Nagano Prefecture, Japan

Yamamoto, Toshiaki, Tamatani, Hiroo, Tanaka, Junpei, Yokoyama, Shotaro, Kamiike, Kumiko, Koyama, Masaru, Seki, Kanako, Kakefuda, Sayoko, Kato, Yuko, Izawa, Natsumi

Journal:

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

7

Annual and seasonal home range characteristics of female Asiatic black bears in Karuizawa, Nagano Prefecture, Japan

Toshiaki Yamamoto, Hiroo Tamatani, Junpei Tanaka, Shotaro Yokoyama, Kumiko Kamiike, Masaru Koyama, Kanako Seki, Sayoko Kakefuda, Yuko Kato and Natsumi Izawa

Journal:

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

8

Studies on the Sulfite and Heat Resistance of Clostridia Responsible for Flat Sour Spoilage of Canned Foods

YAMAMOTO, Kazunori, KAMIYA, Takahisa, KOMURO, Michihiko, KAKEFUDA, Shigeko, MURAKAMI, Ritsuko, ICHIJO, Goro

Journal:

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)

Year:

1988

Language:

english

File:

PDF, 572 KB

english, 1988

9

Corrigendum: Entire CD3ε, δ, and γ humanized mouse to evaluate human CD3–mediated therapeutics

Ueda, Otoya, Wada, Naoko A., Kinoshita, Yasuko, Hino, Hiroshi, Kakefuda, Mami, Ito, Tsuneo, Fujii, Etsuko, Noguchi, Mizuho, Sato, Kiyoharu, Morita, Masahiro, Tateishi, Hiromi, Matsumoto, Kaoru, Goto,

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 120 KB

english, 2018

10

ChemInform Abstract: Synthesis of Novel Succinamide Derivatives Having the 5,11-Dihydro-6H- pyrido(2,3-b)(1,4)benzodiazepin-6-one Skeleton as Potent and Selective M2 Muscarinic Receptor Antagonists. Part 1.

T. WATANABE, I. KINOYAMA, A. KAKEFUDA, T. OKAZAKI, K. TAKIZAWA, S. HIRANO, H. SHIBATA, I. YANAGISAWA

Journal:

Year:

1997

File:

PDF, 31 KB

1997

11

ChemInform Abstract: Synthesis of Novel Succinamide Derivatives Having a 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Skeleton as Potent and Selective M2 Muscarinic Receptor Antagonists. Part 2.

T. WATANABE, A. KAKEFUDA, I. KINOYAMA, K. TAKIZAWA, S. HIRANO, H. SHIBATA, I. YANAGISAWA

Journal:

Year:

1998

File:

PDF, 36 KB

1998

12

ChemInform Abstract: Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. Part 2. Syntheses and NK2 Receptor-Antagonistic Activities of N-[2-Aryl-4-(spiro-substituted piperidin-1′-yl)butyl]carboxamides.

H. KUBOTA, A. KAKEFUDA, H. NAGAOKA, O. YAMAMOTO, K. IKEDA, M. TAKEUCHI, T. SHIBANUMA, Y. ISOMURA

Journal:

Year:

1998

File:

PDF, 32 KB

1998

13

ChemInform Abstract: Synthesis and Biological Evaluation of Phenylacetyl Derivatives Having Low Central Nervous System Permeability as Potent and Selective M2 Muscarinic Receptor Antagonists.

T. WATANABE, A. KAKEFUDA, A. TANAKA, K. TAKIZAWA, S. HIRANO, H. SHIBATA, Y. YAMAGIWA, I. YANAGISAWA

Journal:

Year:

1998

File:

PDF, 44 KB

1998

14

ChemInform Abstract: An Efficient Synthesis of (.+-.)-6,7-Dimethoxy-1-oxo-2- (3-piperidyl)-1,2,3,4-tetrahydroisoquinoline.

Akio Kakefuda, Toshihiro Watanabe, Takumi Takahashi, Shuichi Sakamoto, Shin-Ichi Tsukamoto

Journal:

Year:

2001

File:

PDF, 33 KB

2001

15

ChemInform Abstract: N-Methylbenzanilide Derivatives as a Novel Class of Selective V1A Receptor Antagonists.

Akio Kakefuda, Junko Tsukada, Toshiyuki Kusayama, Atsuo Tahara, Shin-ichi Tsukamoto

Journal:

Year:

2002

File:

PDF, 37 KB

2002

16

Synthesis and Pharmacological Evaluation of 2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinoline Derivatives as Specific Bradycardic Agents.

Akio Kakefuda, Toshihiro Watanabe, Yasuko Taguchi, Noriyuki Masuda, Akihiro Tanaka, Isao Yanagisawa

Journal:

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

17

(.+-.)-2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinolines as a New Class of Specific Bradycardic Agents.

Hideki Kubota, Akio Kakefuda, Toshihiro Watanabe, Yasuko Taguchi, Noe Ishii, Noriyuki Masuda, Shuichi Sakamoto, Shin-ichi Tsukamoto

Journal:

Year:

2003

File:

PDF, 72 KB

2003

18

Discovery of N-(3-{4-[(3-Fluorobenzyl)oxy]phenoxy}propyl)-2-pyridin-4-ylacetamide as a Potent and Selective Reverse NCX Inhibitor.

Takahiro Kuramochi, Akio Kakefuda, Hiroyoshi Yamada, Takashi Ogiyama, Taku Taguchi, Shuichi Sakamoto

Journal:

Year:

2006

File:

PDF, 16 KB

2006

19

Synthesis and pharmacological evaluation of N-acyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel specific bradycardic agents

Hideki Kubota, Toshihiro Watanabe, Akio Kakefuda, Noriyuki Masuda, Kouichi Wada, Noe Ishii, Shuichi Sakamoto, Shinichi Tsukamoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

20

Synthesis and structure–activity relationships of phenoxypyridine derivatives as novel inhibitors of the sodium–calcium exchanger

Takahiro Kuramochi, Akio Kakefuda, Hiroyoshi Yamada, Ippei Sato, Taku Taguchi, Shuichi Sakamoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 421 KB

english, 2004

21

Synthesis and structure–activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: effects on heart failure

Takahiro Kuramochi, Akio Kakefuda, Hiroyoshi Yamada, Takashi Ogiyama, Taku Taguchi, Shuichi Sakamoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 391 KB

english, 2005

22

Synthesis and structure–activity relationships of 6-{4-[(3-fluorobenzyl)oxy]phenoxy}nicotinamide derivatives as a novel class of NCX inhibitors: a QSAR study

Takahiro Kuramochi, Akio Kakefuda, Ippei Sato, Issei Tsukamoto, Taku Taguchi, Shuichi Sakamoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 318 KB

english, 2005

23

Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor

Takahiro Kuramochi, Akio Kakefuda, Hiroyoshi Yamada, Issei Tsukamoto, Taku Taguchi, Shuichi Sakamoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 454 KB

english, 2005

24

Synthesis and biological activity of novel 4,4-difluorobenzazepine derivatives as non-peptide antagonists of the arginine vasopressin V1A receptor

Yoshiaki Shimada, Nobuaki Taniguchi, Akira Matsuhisa, Hiroaki Akane, Noriyuki Kawano, Takeshi Suzuki, Takahiko Tobe, Akio Kakefuda, Takeyuki Yatsu, Atsuo Tahara, Yuichi Tomura, Toshiyuki Kusayama, Koh

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 370 KB

english, 2006

25

Child restraint seat use behavior and attitude among Japanese mothers

Itsumi Kakefuda, Tatsuhiro Yamanaka, Lorann Stallones, Yoichi Motomura, Yoshifumi Nishida

Journal:

Accident Analysis & Prevention

Year:

2008

Language:

english

File:

PDF, 377 KB

english, 2008

26

Synthesis and pharmacological evaluation of piperidinoalkanoyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel specific bradycardic agents

Hideki Kubota, Toshihiro Watanabe, Akio Kakefuda, Noriyuki Masuda, Kouichi Wada, Noe Ishii, Shuichi Sakamoto, Shin-ichi Tsukamoto

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 260 KB

english, 2004

27

Characteristic energy band values and electron attenuation length of a chemical-vapor-deposition diamond (0 0 1)2 × 1 surface

S. Kono, T. Saitou, H. Kawata, T. Goto, Y. Kakefuda, T. Komeda

Journal:

Surface Science

Year:

2009

Language:

english

File:

PDF, 515 KB

english, 2009

28

Band diagram for chemical vapor deposition diamond surface conductive layer: Presence of downward band bending due to shallow acceptors

S. Kono, T. Saito, S.H. Kang, W.Y. Jung, B.Y. Kim, H. Kawata, T. Goto, Y. Kakefuda, H.W. Yeom

Journal:

Surface Science

Year:

2010

Language:

english

File:

PDF, 3.68 MB

english, 2010

29

Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition

David B. Freeman, Alexandra A. Holubec, Matthew W. Weiss, Julie A. Dixon, Akio Kakefuda, Masami Ohtsuka, Munenori Inoue, Rishi G. Vaswani, Hidenori Ohki, Brian D. Doan, Sarah E. Reisman, Brian M. Stol

Journal:

Year:

2010

Language:

english

File:

PDF, 896 KB

english, 2010

30

Electronic states and chemical reactivity of Si(1 0 0)c(4 × 2) surface at low temperature studied by high resolution Si 2p core level photoelectron spectroscopy

S. Machida, M. Nagao, S. Yamamoto, Y. Kakefuda, K. Mukai, Y. Yamashita, J. Yoshinobu

Journal:

Surface Science

Year:

2003

Language:

english

File:

PDF, 346 KB

english, 2003

31

Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol

Akio Kakefuda, Satoshi Shuto, Takemitsu Nagahata, Jun-ichi Seki, Takuma Sasaki, Akira Matsuda

Journal:

Year:

1994

Language:

english

File:

PDF, 1.21 MB

english, 1994

32

Nucleosides and nucleotides. 120. Stereoselective radical deoxygenation of tert-alcohols in the sugar moiety of nucleosides: synthesis of 2′,3′-dideoxy-2′-C-methyl- -2′-C-ethynyl-β-d-threo-pentofuranosyl pyrimidines and adenine as potential antiviral and antitumor agents

Akio Kakefuda, Yuichi Yoshimura, Takuma Sasaki, Akira Matsuda

Journal:

Year:

1993

Language:

english

File:

PDF, 1.17 MB

english, 1993

33

N-Methylbenzanilide derivatives as a novel class of selective V1A receptor antagonists

Akio Kakefuda, Junko Tsukada, Toshiyuki Kusayama, Atsuo Tahara, Shin-ichi Tsukamoto

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

34

(±)-2-(3-Piperidyl)-1,2,3,4-tetrahydroisoquinolines as a new class of specific bradycardic agents

Hideki Kubota, Akio Kakefuda, Toshihiro Watanabe, Yasuko Taguchi, Noe Ishii, Noriyuki Masuda, Shuichi Sakamoto, Shin-ichi Tsukamoto

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 154 KB

english, 2003

35

Discovery of 4,5-Diphenyl-1,2,4-triazole Derivatives as a Novel Class of Selective Antagonists for the Human V1A Receptor

Akio Kakefuda, Takeshi Suzuki, Takahiko Tobe, Atsuo Tahara, Shuichi Sakamoto, Shin-ichi Tsukamoto

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 174 KB

english, 2002

36

Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720

X.-K. Li, A. Tamura, M. Fujino, L. Guo, T. Kakefuda, N. Funeshima, S. Enosawa, M. Amari, S. Naoe, H. Amemiya, S. Suzuki

Journal:

Clinical & Experimental Immunology

Year:

2001

Language:

english

File:

PDF, 497 KB

english, 2001

37

Molecular cloning and expression of the gene encoding ADP-glucose pyrophosphorylase from the cyanobacteriumAnabaenasp. strain PCC 7120

Yee-yung Charng, Genichi Kakefuda, Alberto A. Iglesias, William J. Buikema, Jack Preiss

Journal:

Plant Molecular Biology

Year:

1992

Language:

english

File:

PDF, 1008 KB

english, 1992

38

Chloroplast and extrachloroplastic starch-degrading enzymes inPisum sativumL.

G. Kakefuda, S. H. Duke, M. S. Hostak

Journal:

Year:

1986

Language:

english

File:

PDF, 1.45 MB

english, 1986

39

Involvement of arginine residues in the allosteric activation and inhibition ofSynechocystisPCC 6803 ADPglucose pyrophosphorylase

Alberto A. Iglesias, Genichi Kakefuda, Jack Preiss

Journal:

The Protein Journal

Year:

1992

Language:

english

File:

PDF, 971 KB

english, 1992

40

Nitrosyl hemoglobin detected by near-infrared spectroscopy in rat liver allografts

Toshihiro Kakefuda, Shin Enosawa, Xiao-Kang Li, Akihiko Tamura, Naoko Funeshima, Masaru Kanashiro, Hiroshi Amemiya, Masaki Kitajima, S. Suzuki

Journal:

Transplant International

Year:

1999

Language:

english

File:

PDF, 264 KB

english, 1999

41

Primary non-Hodgkin’s lymphoma of the main hepatic duct junction

Masaya Shito, Toshihiro Kakefuda, Tai Omori, Seiichiro Ishii, Hitoshi Sugiura

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

2008

Language:

english

File:

PDF, 284 KB

english, 2008

42

Electrophoretic properties of low molecular weight DNA fragments in agarose-acrylamide gels

C. Wesley Dingman, T. Kakefuda, M. Patricia Fisher

Journal:

Analytical Biochemistry

Year:

1972

Language:

english

File:

PDF, 587 KB

english, 1972

43

Nucleosides and nucleotides. 147. Synthesis of DNA dodecamers containing oxetanocin A and (2R, 3R)-2-C-(adenin-9-yl)-1,4-anhydro-2,3-dideoxy-3-C-hydroxymethyl-D-arabitol

Akio Kakefuda, Akira Masuda, Yoshihito Ueno, Akira Ono, Akira Matsuda

Journal:

Year:

1996

Language:

english

File:

PDF, 773 KB

english, 1996

44

Discrepancy in bicycle helmet use among college students between two bicycle use purposes: Commuting and recreation

Itsumi Kakefuda, Lorann Stallones, Julie Gibbs

Journal:

Accident Analysis & Prevention

Year:

2009

Language:

english

File:

PDF, 240 KB

english, 2009

45

Fabrication and analysis of buried iron silicide microstructures using a focused low energy electron beam

Youhei Kakefuda, Yoshiyuki Yamashita, Kozo Mukai, Jun Yoshinobu

Journal:

Surface Science

Year:

2007

Language:

english

File:

PDF, 434 KB

english, 2007

46

Role of the testa epidermis in the leakage of intracellular substances from imbibing soybean seeds and its implications for seedling survival

Stanley H. Duke, Genichi Kakefuda, Cynthia A. Henson, Nancy L. Loeffler, Nancy M. Van Hulle

Journal:

Physiologia Plantarum

Year:

1986

Language:

english

File:

PDF, 584 KB

english, 1986

47

An immunosuppressive regimen using FTY720 combined with cyclosporine in canine kidney transplantation

Seiichi Suzuki, Toshihiro Kakefuda, Hiroshi Amemiya, Kenji Chiba, Yukio Hoshino, Takafumi Kawaguchi, Hirotoshi Kataoka, Fazlur Rahman

Journal:

Transplant International

Year:

1998

Language:

english

File:

PDF, 497 KB

english, 1998

48

Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY720, in rat small bowel transplantation

Makoto Mitsusada, Seiichi Suzuki, Eiji Kobayashi, Shin Enosawa, Toshihiro Kakefuda, Michio Miyata

Journal:

Transplant International

Year:

1997

Language:

english

File:

PDF, 529 KB

english, 1997

49

Nitrosyl hemoglobin detected by near-infrared spectroscopy in rat liver allografts

TOSHIHIRO Kakefuda, SHIN Enosawa, XIAO-KANG Li, AKIHIKO Tamura, NAOKO Funeshima, MASARU Kanashiro, HIROSHI Amemiya, MASAKI Kitajima, SEIICHI Suzuki

Journal:

Transplant International

Year:

1999

Language:

english

File:

PDF, 2.14 MB

english, 1999

50

Location of non-DNA components of closed circular colicin E1 plasmid DNA

SUGINO, YOSHINOBU, TOMIZAWA, JUN-ICHI, KAKEFUDA, TSUYOSHI

Journal:

Year:

1975

File:

PDF, 625 KB

1975

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